1. the disgrace, the embarrassment (VERY strong and epic word. The kind that gets you disowned :))
Opposite (closest): Ehre
A fun look at the meaning of "peinlich", how to say that you're embarrassed in German and some more words like shame or disgrace :).
Vocab:
peinlich, die Pein, der Schmerz, das Schmerzmittel, die Schande, bloßstellen, sich blamieren